UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Is MDMA ('ecstasy') neurotoxic in humans? An overview of evidence and of methodological problems in research

Curran, HV; (2000) Is MDMA ('ecstasy') neurotoxic in humans? An overview of evidence and of methodological problems in research. NEUROPSYCHOBIOLOGY , 42 (1) 34 - +.

Full text not available from this repository.

Abstract

Evidence from research with a range of animal species, from rodents to non-human primates, has shown that MDMA (+/- 3,4-methylenedioxymethamphetamine) is neurotoxic, This article explores the evidence that MDMA may be neurotoxic in humans by briefly over-viewing three types of research: (1) neurobiological, (2) psychological/somatic and (3) psychiatric. The first type of evidence derives from neuropharmacological and neuroendocrine studies, the second type focuses on psychological function and somatic symptoms in MDMA users, and the third involves studies of psychiatric cases in people who have taken MDMA. Evidence from these types of studies is indirect and differs in the degree to which any causative links are implied between observed effects, MDMA use and human neurotoxicity, These issues are critically discussed within the context of the wide-ranging methodological problems in human research with MDMA, Copyright (C) 2000 S. Karger AG, Basel.

Type: Article
Title: Is MDMA ('ecstasy') neurotoxic in humans? An overview of evidence and of methodological problems in research
Location: BASEL, SWITZERLAND
Keywords: MDMA, ecstasy, neurobiology, neurotoxicity, cognitive function, memory, mood, methods, evidence, 3,4-METHYLENEDIOXYMETHAMPHETAMINE MDMA, (+/-)3,4-METHYLENEDIOXYMETHAMPHETAMINE MDMA, SUBJECTIVE REPORTS, NORMAL VOLUNTEERS, MEMORY DEFICITS, MOOD, TRYPTOPHAN, DEPLETION, SEQUELAE, NEURONS
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
URI: http://discovery.ucl.ac.uk/id/eprint/105020
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item