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LIPOSOME-MEDIATED DELIVERY STIMULATES A CLASS-I-RESTRICTED CYTOTOXIC T-CELL RESPONSE TO SOLUBLE-ANTIGEN

LOPES, LM; CHAIN, BM; (1992) LIPOSOME-MEDIATED DELIVERY STIMULATES A CLASS-I-RESTRICTED CYTOTOXIC T-CELL RESPONSE TO SOLUBLE-ANTIGEN. EUR J IMMUNOL , 22 (1) 287 - 290.

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Abstract

Most soluble protein antigens are poor at priming class I-restricted cytotoxic cell activity. In this study we show that incorporation of one protein, ovalbumin, into liposomes converts this antigen into an effective stimulator of antigen-specific cytotoxicity. The mechanisms responsible for this phenomenon are discussed.

Type: Article
Title: LIPOSOME-MEDIATED DELIVERY STIMULATES A CLASS-I-RESTRICTED CYTOTOXIC T-CELL RESPONSE TO SOLUBLE-ANTIGEN
Keywords: TOXIC LYMPHOCYTES-T, PHOSPHOLIPID-VESICLES, INDUCTION, INVITRO, INVIVO, VIRUS
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science
URI: http://discovery.ucl.ac.uk/id/eprint/103332
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