Komssi, S; Savolainen, P; Heiskala, J; Kähkönen, S; (2007) Excitation threshold of the motor cortex estimated with transcranial magnetic stimulation electroencephalography. NeuroReport , 18 (1) 13 - 16.
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The excitation threshold of the human motor cortex (M1) was estimated on the basis of electroencephalographic (EEG) responses evoked by transcranial magnetic stimulation (TMS). The hand area of M1 (n = 7) was stimulated at ten intensities. The four dominant peaks of the overall brain response were reliably determined when stimulation intensity was 40% of the motor threshold, the probability of identifying each peak ranging between 0.71 and 0.86. Therefore, the cortical electric field of 33–44 mV/mm, approximately being induced with this intensity, may be estimated as the threshold for evoking measurable brain activity by motor-cortex TMS. As TMS–EEG enables the assessment of cortical reactivity with excellent sensitivity, it seems justified to move over to lower stimulation intensities, for increased safety.
|Title:||Excitation threshold of the motor cortex estimated with transcranial magnetic stimulation electroencephalography|
|Keywords:||transcranial magnetic stimulation, motor cortex, electroencephalography, evoked potential|
|UCL classification:||UCL > School of BEAMS > Faculty of Engineering Science > Computer Science|
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