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Significance of tissue anisotropy in optical tomography of the infant brain

Heiskala, J; Neuvonen, T; Grant, PE; Nissilä, I; (2007) Significance of tissue anisotropy in optical tomography of the infant brain. Applied Optics , 46 (10) 1633 - 1640.

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Abstract

We study the effect of tissue anisotropy in optical tomography of neonates. A Monte Carlo method capable of modeling photon migration in an arbitrary 3D tissue model with spatially varying optical properties and tissue anisotropy is used for simulating measurements of neonates. Anatomical and diffusion tensor magnetic resonance imaging of neonates are used for creating the anatomical models. We find that tissue anisotropy affects the measured signal and the pattern of sensitivity in optical measurements.

Type:Article
Title:Significance of tissue anisotropy in optical tomography of the infant brain
Keywords:diffuse optical imaging, anisotropy
UCL classification:UCL > School of BEAMS > Faculty of Engineering Science > Computer Science

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