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Iron deficiency in chronic heart failure: case-based practical guidance

Lam, CSP; Doehner, W; Comin-Colet, J; IRON CORE Group, .; (2018) Iron deficiency in chronic heart failure: case-based practical guidance. ESC Heart Failure , 5 (5) pp. 764-771. 10.1002/ehf2.12333. Green open access

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Abstract

In patients with chronic heart failure, iron deficiency, even in the absence of anaemia, can aggravate the underlying disease and have a negative impact on clinical outcomes and quality of life. The 2016 European Society of Cardiology guidelines for the diagnosis and treatment of acute and chronic heart failure recognize iron deficiency as a co-morbidity in chronic heart failure and recommend iron status screening in all newly diagnosed patients with chronic heart failure. Furthermore, the guidelines specifically recommend considerations of intravenous iron therapy, ferric carboxymaltose, for the treatment of iron deficiency. However, in spite of these recommendations, iron deficiency remains often overlooked and undertreated. This may be due, in part, to the lack of clinical context and practical guidance accompanying the guidelines for the treating physician. Here, we provide practical guidance complemented by a case study to assist and improve the timely diagnosis, treatment, and routine management of iron deficiency in patients with chronic heart failure.

Type: Article
Title: Iron deficiency in chronic heart failure: case-based practical guidance
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/ehf2.12333
Publisher version: https://doi.org/10.1002/ehf2.12333
Language: English
Additional information: © 2018 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
Keywords: Iron deficiency, Chronic heart failure, Practical guidance, Ferric carboxymaltose, Case study
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health
URI: https://discovery.ucl.ac.uk/id/eprint/10068990
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