UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Therapies to Slow, Stop, or Reverse Parkinson's Disease

Foltynie, T; Langston, JW; (2018) Therapies to Slow, Stop, or Reverse Parkinson's Disease. Journal of Parkinson's Disease , 8 (s1) S115-S121. 10.3233/JPD-181481. Green open access

[img]
Preview
Text
jpd%2F2018%2F8-s1%2Fjpd-8-s1-jpd181481%2Fjpd-8-jpd181481-1.pdf - ["content_typename_Published version" not defined]

Download (185kB) | Preview

Abstract

Our understanding of PD pathophysiology is vastly improved compared to the situation 20 years ago. We have identified the major genetic risks for PD, we now have far more representative animal models of the disease, and we can be inspired by the early successes of others using Antisense Oligonucleotide and vaccination approaches in other neurodegenerative diseases. We also have a broad range of repurposed drugs showing the first signals of potential efficacy in the translational pipeline which are being driven forward through the various clinical trial stages. We believe we can be optimistic that the next 20 years will be a time for major breakthroughs towards the discovery of therapies that may slow, stop, or reverse PD.

Type: Article
Title: Therapies to Slow, Stop, or Reverse Parkinson's Disease
Location: Netherlands
Open access status: An open access version is available from UCL Discovery
DOI: 10.3233/JPD-181481
Publisher version: http://doi.org/10.3233/JPD-181481
Language: English
Additional information: Copyright © 2018 – IOS Press and the authors. All rights reserved. This article is published online with Open Access and distributed under the terms of the Creative Commons Attribution Non-Commercial License (CC BY-NC 4.0).
Keywords: Parkinson’s disease, disease-modifying, neuroprotection
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Movement Neurosciences
URI: http://discovery.ucl.ac.uk/id/eprint/10064991
Downloads since deposit
115Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item