Larson, SD;
Gleeson, P;
Brown, AEX;
(2018)
Connectome to behaviour: modelling Caenorhabditis elegans at cellular resolution.
Philosophical Transactions B: Biological Sciences
, 373
(1758)
10.1098/rstb.2017.0366.
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Abstract
It has been 30 years since the ‘mind of the worm’ was published in Philosophical Transactions B (White et al. 1986 Phil. Trans. R. Soc. Lond. B 314, 1–340). Predicting Caenorhabditis elegans' behaviour from its wiring diagram has been an enduring challenge since then. This special theme issue of Philosophical Transactions B combines research from neuroscientists, physicists, mathematicians and engineers to discuss advances in neural activity imaging, behaviour quantification and multiscale simulations, and how they are bringing the goal of whole-animal modelling at cellular resolution within reach. This article is part of a discussion meeting issue ‘Connectome to behaviour: modelling C. elegans at cellular resolution’.
| Type: | Article |
|---|---|
| Title: | Connectome to behaviour: modelling Caenorhabditis elegans at cellular resolution |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1098/rstb.2017.0366 |
| Publisher version: | https://doi.org/10.1098/rstb.2017.0366 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Science & Technology, Life Sciences & Biomedicine, Biology, Life Sciences & Biomedicine - Other Topics, nervous system, open data, simulation, Caenorhabditis elegans, connectome, behaviour, C. ELEGANS, WORM |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Neuro, Physiology and Pharmacology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10058221 |
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