Barona, M;
Taborelli, E;
Corfield, F;
Pawlby, S;
Easter, A;
Schmidt, U;
Treasure, J;
(2017)
Neurobehavioural and cognitive development in infants born to mothers with eating disorders.
Journal of Child Psychology and Psychiatry and Allied Disciplines
, 58
(8)
pp. 931-938.
10.1111/jcpp.12736.
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Abstract
INTRODUCTION: Although recent research has focused on the effects of maternal eating disorders (EDs) on children, little is known about the effect of maternal EDs on neurobiological outcomes in newborns and infants. This study is the first to investigate neurobehavioural regulation and cognitive development in newborns and infants of mothers with EDs. METHODS: Women with an active and past ED and healthy controls were recruited to a prospective longitudinal study during their first trimester or second trimester of pregnancy. Newborns and infants of mothers with ED were compared with newborns and infants of healthy controls on (a) neurobehavioural dysregulation using the Brazelton Neonatal Behavioural Assessment Scale at 8 days postpartum (active ED, n = 15; past ED, n = 20; healthy controls, n = 28); and (b) cognitive development using the Bayley Scales of Infant and Toddler Development at 1‐year postpartum (active ED, n = 18; past ED, n = 19; healthy controls, n = 28). In order to maintain the largest possible sample at each time point, sample size varied across time points. RESULTS: Newborns of mothers with an active ED had worse autonomic stability when compared with newborns of healthy controls [B = −0.34 (−1.81, −0.26)]. Infants of mothers with a past ED had poorer language [B = −0.33 (−13.6, −1.9)] and motor development [B = −0.32 (−18.4, −1.3)] compared with healthy controls. CONCLUSIONS: Children of mothers with ED display neurobehavioural dysregulation early after birth and poorer language and motor development at 1 year. These characteristics suggest evidence of early neurobiological markers in children at risk. Differential outcomes in children of women with active versus past ED suggest that active symptomatology during pregnancy might have an effect on physiological reactivity while cognitive characteristics might be more stable markers of risk for ED.
| Type: | Article |
|---|---|
| Title: | Neurobehavioural and cognitive development in infants born to mothers with eating disorders |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/jcpp.12736 |
| Publisher version: | http://dx.doi.org/10.1111/jcpp.12736 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Social Sciences, Science & Technology, Life Sciences & Biomedicine, Psychology, Developmental, Psychiatry, Psychology, Brazelton Neonatal Behavioural Assessment Scale, Bayley Scales of Infant and Toddler Development, eating disorders, child development, CHILDHOOD PSYCHOPATHOLOGY, GENERAL-POPULATION, CHILDREN, WOMEN, PREGNANCY, DEPRESSION, RISK, ANXIETY, SYMPTOMS, NERVOSA |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10057571 |
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