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Upconversion nanocrystal "armoured' silica fibres with superior photoluminescence for miRNA detection

Wang, G; Fu, Y; Ren, Z; Huang, J; Best, S; Li, X; Han, G; (2018) Upconversion nanocrystal "armoured' silica fibres with superior photoluminescence for miRNA detection. Chemical Communications , 54 (49) pp. 6324-6327. 10.1039/c8cc03480j. Green open access

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Abstract

We have fabricated a flexible membrane, consisting of SiO2 nanofibres armoured with upconversion nanoparticles, exhibiting intense photoluminescence. These assemblies were subsequently grafted with molecular beacons to produce a biosensor suitable for the detection of specific microRNA and with applications in early cancer detection and point-of-care diagnosis.

Type: Article
Title: Upconversion nanocrystal "armoured' silica fibres with superior photoluminescence for miRNA detection
Open access status: An open access version is available from UCL Discovery
DOI: 10.1039/c8cc03480j
Publisher version: https://doi.org/10.1039/c8cc03480j
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions
Keywords: Science & Technology, Physical Sciences, Chemistry, Multidisciplinary, Chemistry, RESONANCE ENERGY-TRANSFER, FLUORESCENCE DETECTION, NANOFIBROUS MEMBRANES, MICRORNA DETECTION, DRUG-DELIVERY, NANOPARTICLES, CANCER, PROBES, HYBRIDIZATION, AMPLIFICATION
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering
URI: http://discovery.ucl.ac.uk/id/eprint/10055388
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