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Direct ink writing of highly bioactive glasses

Nommeots-Nomm, A; Lee, PD; Jones, JR; (2018) Direct ink writing of highly bioactive glasses. Journal of the European Ceramic Society , 38 (3) pp. 837-844. 10.1016/j.jeurceramsoc.2017.08.006. Green open access

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Abstract

Direct ink writing (DIW), or Robocasting, is an additive manufacturing technique that offers the opportunity to create patient specific bioactive glass scaffolds and high strength scaffolds for bone repair. The original 45S5 Bioglass®composition crystallises during sintering and until now, robocast glass scaffolds contained at least 51.9 mol% SiO2or B2O3to maintain their amorphous structure. Here, ICIE16 and PSrBG compositions, containing <50 mol% SiO2, giving silicate network connectivity close to that of 45S5, were robocast and compared to 13–93 composition. Results showed Pluronic F-127 can be used as a universal binder regardless of glass reactivity and that particle size distribution affected the ink “printability”. Scaffolds with interconnects of 150 μm (41–43% porosity) had compressive strengths of 32–48 MPa, depending on the glass composition. Robocast scaffolds from these highly reactive bioactive glasses promise greatly improved bone regeneration rates compared with existing bioactive glass scaffolds.

Type: Article
Title: Direct ink writing of highly bioactive glasses
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.jeurceramsoc.2017.08.006
Publisher version: http://doi.org/10.1016/j.jeurceramsoc.2017.08.006
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Robocasting, Direct ink writing, Scaffold, Bioglass, Amorphous, Bone repair
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering
URI: http://discovery.ucl.ac.uk/id/eprint/10053481
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