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Isolated insulin-derived amyloidoma of the breast

Mayhew, JM; Alan, T; Kalidindi, V; Gandamihardja, TAK; (2017) Isolated insulin-derived amyloidoma of the breast. BMJ Case Reports , 2017 10.1136/bcr-2017-219491. Green open access

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Abstract

Isolated amyloidomas derived from insulin are extremely rare, and there is only one reported case to date of insulin-derived amyloidoma in the breast.We present the case of a 36-year-old woman reporting a lump in the right breast. It was clinically assessed as a probable fibroadenoma but was removed surgically given the size of the lesion. On histological analysis, the lesion had features consistent with amyloid. Further investigations showed the amyloid to be derived from insulin. The lump was removed in its entirety, and the patient made a full recovery.

Type: Article
Title: Isolated insulin-derived amyloidoma of the breast
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/bcr-2017-219491
Publisher version: http://dx.doi.org/10.1136/bcr-2017-219491
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Breast surgery, Pathology, Adult, Amyloid, Amyloidosis, Breast, Breast Neoplasms, Diagnosis, Differential, Female, Fibroadenoma, Humans, Insulin, Rare Diseases, Treatment Outcome, Ultrasonography
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > UCL Medical School
URI: http://discovery.ucl.ac.uk/id/eprint/10051744
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