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On the Road from Gene to Therapy in Inherited Cardiomyopathies Preface

Limongelli, G; Bossone, E; Elliott, PM; Day, SM; (2018) On the Road from Gene to Therapy in Inherited Cardiomyopathies Preface. [Editorial comment]. Heart Failure Clinics , 14 (2) XI-XV. 10.1016/j.hfc.2018.01.003.

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Abstract

Almost 30 years after the discovery of the first genetic mutation for HCM, the development of new pharmacological approaches targeting cardiomyopathies and other orphan/rare cardiac disease is becoming closer to reality. Development of targeted therapies is enabled by new insights into the clinical and molecular aspects, and pathogenesis of cardiomyopathies, along with the establishment of large-scale international collaboration and the increasing engagement of the pharmaceutical industry. The road toward “cardiovascular precision medicine” is just beginning, with inherited and rare diseases leading the way in this exciting new era.

Type: Article
Title: On the Road from Gene to Therapy in Inherited Cardiomyopathies Preface
DOI: 10.1016/j.hfc.2018.01.003
Publisher version: http://doi.org/10.1016/j.hfc.2018.01.003
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: inherited cardiomyopathies, genetics, therapy, precision medicine
URI: http://discovery.ucl.ac.uk/id/eprint/10049862
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