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A case of pure gelastic seizures due to hypothalamic hamartoma with a benign course

Gosavi, TD; Walker, MC; (2017) A case of pure gelastic seizures due to hypothalamic hamartoma with a benign course. Epilepsy and Behavior Case Reports , 8 pp. 111-113. 10.1016/j.ebcr.2017.06.004. Green open access

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Abstract

Hypothalamic hamartoma is a potentially complex entity with diverse clinical manifestations. We report a case of gelastic seizures associated with a hypothalamic hamartoma, which followed a benign course. A 31-year-old woman with episodes of laughter was referred for diagnostic evaluation. Her initial MRI and EEG were reported as normal. However, her episodes of laughter were typical of gelastic seizures from history and video review. Repeat MRI revealed a small HH. She declined any medical treatment and was medication free until last follow-up. This benign course of HH-associated epilepsy, not necessitating treatment, to our knowledge, has not been previously reported.

Type: Article
Title: A case of pure gelastic seizures due to hypothalamic hamartoma with a benign course
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.ebcr.2017.06.004
Publisher version: https://doi.org/10.1016/j.ebcr.2017.06.004
Language: English
Additional information: Copyright © 2017 The Authors. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Keywords: Gelastic seizures, Hypothalamic hamartoma, Benign outcome
URI: http://discovery.ucl.ac.uk/id/eprint/10048570
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