Nascimento, CDM;
Oliveira, CD;
Firmo, JO;
Lima-Costa, MF;
Peixoto, SV;
(2018)
Prognostic value of disability on mortality: 15-year follow-up of the Bambuí Cohort Study of Aging.
Archives of Gerontology and Geriatrics
, 74
pp. 112-117.
10.1016/j.archger.2017.10.011.
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Abstract
BACKGROUND: Disability is a concern in the context of population ageing. The extent of an individual’s disability is a major determinant of whether or not they require long-term care or survival time. We investigated the effect of three disability domains as predictors of all-cause mortality over 15-year follow-up in a Brazilian socioeconomically disadvantaged and multiracial older adult population. METHODS: We estimated Cox proportional hazards models using data from 1333 community-dwelling individuals aged 60 and older from the Bambuí Cohort Study of Ageing. Disability was defined as a great difficulty or not being able to perform one and two or more activities in each domain: mobility, instrumental activities of daily living (IADL) and basic activities of daily living (BADL). RESULTS: The overall mortality rate was 46.1 per 1000 person-years at risk (pyrs) and it was higher in men. Among men, the fully adjusted Hazard Ratios (HRs) were 1.92 (95%CI: 1.43-2.58), 2.07 (95%CI: 1.53-2.79) and 1.65 (95%CI: 1.11-2.45), and among women 1.75 (95%CI: 1.38-2.21), 1.43 (95%CI: 1.11-1.84) and 1.43 (95%CI: 1.05-1.95), for two or more disability in mobility tasks, IADLs and BADLs, respectively, compared to those with no difficulty or some difficulty to perform all the tasks. CONCLUSION: A similar risk of death for mobility, IADL and BADL in both genders was found, suggesting that any of these domains can be used to identify risk of all-cause mortality among older adults. The number of activities with limitations in each domain was an important factor.
| Type: | Article |
|---|---|
| Title: | Prognostic value of disability on mortality: 15-year follow-up of the Bambuí Cohort Study of Aging |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.archger.2017.10.011 |
| Publisher version: | http://doi.org/10.1016/j.archger.2017.10.011 |
| Language: | English |
| Additional information: | © 2017 Elsevier B.V. All rights reserved. This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Mortality; Disability; Cohort studies; Brazil |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10039541 |
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