Bush, D;
Bisby, JA;
Bird, CM;
Gollwitzer, S;
Rodionov, R;
Diehl, B;
McEvoy, AW;
... Burgess, N; + view all
(2017)
Human hippocampal theta power indicates movement onset and distance travelled.
Proceedings of the National Academy of Sciences of the United States of America
, 114
(46)
pp. 12297-12302.
10.1073/pnas.1708716114.
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Abstract
Rodent hippocampal theta-band oscillations are observed throughout translational movement, implicating theta in the encoding of self-motion. Interestingly, increases in theta power are particularly prominent around movement onset. Here, we use intracranial recordings from epilepsy patients navigating in a desktop virtual reality environment to demonstrate that theta power is also increased in the human hippocampus around movement onset and throughout the remainder of movement. Importantly, these increases in theta power are greater both before and during longer paths, directly implicating human hippocampal theta in the encoding of translational movement. These findings help to reconcile previous studies of rodent and human hippocampal theta oscillations and provide additional insight into the mechanisms of spatial navigation in the human brain.
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