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A biologist's guide to Bayesian phylogenetic analysis

Nascimento, FF; Reis, MD; Yang, Z; (2017) A biologist's guide to Bayesian phylogenetic analysis. Nature Ecology and Evolution , 1 (10) pp. 1446-1454. 10.1038/s41559-017-0280-x. Green open access

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Abstract

Bayesian methods have become very popular in molecular phylogenetics due to the availability of user-friendly software for running sophisticated models of evolution. However, Bayesian phylogenetic models are complex, and analyses are often carried out using default settings, which may not be appropriate. Here we summarize the major features of Bayesian phylogenetic inference and discuss Bayesian computation using Markov chain Monte Carlo (MCMC) sampling, the diagnosis of an MCMC run, and ways of summarizing the MCMC sample. We discuss the specification of the prior, the choice of the substitution model and partitioning of the data. Finally, we provide a list of common Bayesian phylogenetic software packages and recommend appropriate applications.

Type: Article
Title: A biologist's guide to Bayesian phylogenetic analysis
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/s41559-017-0280-x
Publisher version: http://dx.doi.org/10.1038/s41559-017-0280-x
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment
URI: https://discovery.ucl.ac.uk/id/eprint/10023391
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